Article
Genome-wide association mapping of acute lung injury in neonatal inbred mice.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology - 1 Jun 2014
Nichols Jennifer L, Gladwell Wesley, Verhein Kirsten C, Cho Hye-Youn, Wess Jürgen, Suzuki Oscar, Wiltshire Tim, Kleeberger Steven R
Abstract excerpt
Reactive oxygen species (ROS) contribute to the pathogenesis of many acute and chronic pulmonary disorders, including bronchopulmonary dysplasia (BPD), a respiratory condition that affects preterm infants. However, the mechanisms of susceptibility to oxidant stress in neonatal lungs are not completely understood. We evaluated the role of genetic background in response to oxidant stress in the neonatal lung by...
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