Article
Acute lung injury: functional genomics and genetic susceptibility.
Chest - 1 Mar 2002
Leikauf George D, McDowell Susan A, Wesselkamper Scott C, Hardie William D, Leikauf John E, Korfhagen Thomas R, Prows Daniel R
Abstract excerpt
Initiated by numerous factors, acute lung injury is marked by epithelial and endothelial cell perturbation and inflammatory cell influx that leads to surfactant disruption, pulmonary edema, and atelectasis. This syndrome has been associated with a myriad of mediators including cytokines, oxidants, and growth factors. To better understand gene-environmental interactions controlling this complex process, the...
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