Article
Genetic mechanisms of susceptibility to oxidative lung injury in mice.
Free radical biology & medicine - 15 Feb 2007
Cho Hye-Youn, Kleeberger Steven R
Abstract excerpt
Genetic background is a known predisposing risk factor for many acute and chronic pulmonary disorders and responses to environmental oxidants. Variation in lung injury responses to oxidative stimuli such as ozone, particles, hyperoxia, and chemotherapeutic agents between genetically standardized inbred mouse strains has been demonstrated. In this review, we discuss quantitative trait loci (QTLs) which contain...
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