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Article

Genetic susceptibility to irritant-induced acute lung injury in mice.

American journal of physiology. Lung cellular and molecular physiology - 1 Sept 2000

Wesselkamper S C, Prows D R, Biswas P, Willeke K, Bingham E, Leikauf G D

Abstract excerpt

Recent studies suggest that genetic variability can influence irritant-induced lung injury and inflammation. To begin identifying genes controlling susceptibility to inhaled irritants, seven inbred mouse strains were continuously exposed to nickel sulfate (NiSO(4)), polytetrafluoroethylene, or ozone (O(3)), and survival time was recorded. The A/J (A) mouse strain was sensitive, the C3H/He (C3) strain was...

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Identifiers

PMID: 10956633
DOI: 10.1152/ajplung.2000.279.3.L575

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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