Article
Genetic analysis of hyperoxic acute lung injury survival in reciprocal intercross mice.
Physiological genomics - 20 Aug 2007
Prows Daniel R, Hafertepen Amanda P, Winterberg Abby V, Gibbons William J, Liu Chunyan, Nick Todd G
Abstract excerpt
Acute lung injury (ALI) and its most severe presentation, acute respiratory distress syndrome, represent a full spectrum of a complex and devastating illness, with associated mortality that still hovers around 30-40%. Even supplemental O2, a routine and necessary therapy for such patients, paradoxically causes lung injury. The detrimental effects of O2 have established hyperoxic ALI (HALI) as a conventional model...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
