Article

Remarkable sex-specific differences at Single-Cell Resolution in Neonatal Hyperoxic Lung Injury

2022-08-19

Abstract excerpt

<h4>ABSTRACT</h4> Exposure to supraphysiological concentrations of oxygen (hyperoxia) predisposes to bronchopulmonary dysplasia (BPD), which is characterized by abnormal alveolarization and pulmonary vascular development, in preterm neonates. Neonatal hyperoxia exposure is used to recapitulate the phenotype of human BPD in murine models. Male sex is considered an independent predictor for the development of BPD,...

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Literature Corpus work: cffda439-daf4-5de1-a609-8d51c708f3d6
DOI: 10.1101/2022.08.19.504541

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