Article
Interaction between adolescent obesity and HLA risk genes in the etiology of multiple sclerosis.
Neurology - 11 Mar 2014
Hedström Anna Karin, Lima Bomfim Izaura, Barcellos Lisa, Gianfrancesco Milena, Schaefer Catherine, Kockum Ingrid, Olsson Tomas, Alfredsson Lars
Abstract excerpt
OBJECTIVE: We investigated potential interactions between human leukocyte antigen (HLA) genotype and body mass index (BMI) status in relation to the risk of developing multiple sclerosis (MS). METHODS: We used 2 case-control studies, one with incident cases (1,510 cases, 2,017 controls) and one with prevalent cases (937 cases, 609 controls). Subjects with different genotypes and BMI were compared with regard to...
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