Article
The interaction between smoking and HLA genes in multiple sclerosis: replication and refinement.
European journal of epidemiology - 1 Oct 2017
Hedström Anna Karin, Katsoulis Michail, Hössjer Ola, Bomfim Izaura L, Oturai Annette, Sondergaard Helle Bach, Sellebjerg Finn, Ullum Henrik, Thørner Lise Wegner, Gustavsen Marte Wendel, Harbo Hanne F, Obradovic Dragana, Gianfrancesco Milena A, Barcellos Lisa F, Schaefer Catherine A, Hillert Jan, Kockum Ingrid, Olsson Tomas, Alfredsson Lars
Abstract excerpt
Interactions between environment and genetics may contribute to multiple sclerosis (MS) development. We investigated whether the previously observed interaction between smoking and HLA genotype in the Swedish population could be replicated, refined and extended to include other populations. We used six independent case-control studies from five different countries (Sweden, Denmark, Norway, Serbia, United States)....
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.