Article
High-allelic variability in HLA-C mRNA expression: association with HLA-extended haplotypes.
Genes and immunity - 1 Jan 2000
Bettens F, Brunet L, Tiercy J-M
Abstract excerpt
Human leukocyte antigen (HLA)-C is a clinically relevant transplantation antigen in unrelated hematopoietic stem cell and cord blood transplantation. Furthermore, HLA-C antigens, as ligands for killer immunoglobulin-like receptors expressed on natural killer cells, have a central role in HIV control. Several studies have reported significant correlations between HLA-C mRNA and cell surface expression with...
Topics
- Alleles
- Gene Expression
- HLA-C Antigens
- Haplotypes
- Humans
- Polymorphism, Single Nucleotide
- RNA, Messenger
