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Article

HLA-E regulatory and coding region variability and haplotypes in a Brazilian population sample.

Molecular immunology - 1 Nov 2017

Ramalho Jaqueline, Veiga-Castelli Luciana C, Donadi Eduardo A, Mendes-Junior Celso T, Castelli Erick C

Abstract excerpt

The HLA-E gene is characterized by low but wide expression on different tissues. HLA-E is considered a conserved gene, being one of the least polymorphic class I HLA genes. The HLA-E molecule interacts with Natural Killer cell receptors and T lymphocytes receptors, and might activate or inhibit immune responses depending on the peptide associated with HLA-E and with which receptors HLA-E interacts to. Variable...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 28946074
DOI: 10.1016/j.molimm.2017.09.007

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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