Article
5' and 3' untranslated regions contribute to the differential expression of specific HLA-A alleles.
European journal of immunology - 1 Dec 2015
René Céline, Lozano Claire, Villalba Martin, Eliaou Jean-François
Abstract excerpt
In hematopoietic stem cell transplantation (HSCT), when no HLA full-matched donor is available, alternative donors could include one HLA-mismatched donor. Recently, the low expressed HLA-C alleles have been identified as permissive mismatches for the best donor choice. Concerning HLA-A, the degree of variability of expression is poorly understood. Here, we evaluated HLA-A expression in healthy individuals...
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