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Article

Circadian rhythms of Per2::Luc in individual primary mouse hepatocytes and cultures.

PloS one - 1 Jan 2014

Guenthner Casey J, Luitje Martha E, Pyle Lorna A, Molyneux Penny C, Yu Jimmy K, Li Alexander S, Leise Tanya L, Harrington Mary E

Abstract excerpt

BACKGROUND: Hepatocytes, the parenchymal cells of the liver, express core clock genes, such as Period2 and Cryptochrome2, which are involved in the transcriptional/translational feedback loop of the circadian clock. Whether or not the liver is capable of sustaining rhythms independent of a central pacemaker is controversial. Whether and how circadian information may be shared among cells in the liver in order to...

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Identifiers

PMID: 24498336
DOI: 10.1371/journal.pone.0087573
PMCID: PMC3911982

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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