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Article

Estimation of the spontaneous mutation rate per nucleotide site in a Drosophila melanogaster full-sib family.

Genetics - 1 Jan 2014

Keightley Peter D, Ness Rob W, Halligan Daniel L, Haddrill Penelope R

Abstract excerpt

We employed deep genome sequencing of two parents and 12 of their offspring to estimate the mutation rate per site per generation in a full-sib family of Drosophila melanogaster recently sampled from a natural population. Sites that were homozygous for the same allele in the parents and heterozygous in one or more offspring were categorized as candidate mutations and subjected to detailed analysis. In 1.23 ×...

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Identifiers

PMID: 24214343
DOI: 10.1534/genetics.113.158758
PMCID: PMC3872194

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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