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Article

Analysis of the genome sequences of three Drosophila melanogaster spontaneous mutation accumulation lines.

Genome research - 1 Jul 2009

Keightley Peter D, Trivedi Urmi, Thomson Marian, Oliver Fiona, Kumar Sujai, Blaxter Mark L

Abstract excerpt

We inferred the rate and properties of new spontaneous mutations in Drosophila melanogaster by carrying out whole-genome shotgun sequencing-by-synthesis of three mutation accumulation (MA) lines that had been maintained by close inbreeding for an average of 262 generations. We tested for the presence of new mutations by generating alignments of each MA line to the D. melanogaster reference genome sequence and...

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Identifiers

PMID: 19439516
DOI: 10.1101/gr.091231.109
PMCID: PMC2704435

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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