Article
Direct estimation of the mitochondrial DNA mutation rate in Drosophila melanogaster.
PLoS biology - 19 Aug 2008
Haag-Liautard Cathy, Coffey Nicole, Houle David, Lynch Michael, Charlesworth Brian, Keightley Peter D
Abstract excerpt
Mitochondrial DNA (mtDNA) variants are widely used in evolutionary genetics as markers for population history and to estimate divergence times among taxa. Inferences of species history are generally based on phylogenetic comparisons, which assume that molecular evolution is clock-like. Between-species comparisons have also been used to estimate the mutation rate, using sites that are thought to evolve neutrally....
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