Article
Molecular nature of 11 spontaneous de novo mutations in Drosophila melanogaster.
Genetics - 1 Mar 2001
Yang H P, Tanikawa A Y, Kondrashov A S
Abstract excerpt
To investigate the molecular nature and rate of spontaneous mutation in Drosophila melanogaster, we screened 887,000 individuals for de novo recessive loss-of-function mutations at eight loci that affect eye color. In total, 28 mutants were found in 16 independent events (13 singletons and three clusters). The molecular nature of the 13 events was analyzed. Coding exons of the locus were affected by insertions or...
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