Molecular spectrum of spontaneous de novo mutations in male and female germline cells of Drosophila melanogaster.

Abstract excerpt

We carried out mutation screen experiments to understand the rate and molecular nature of spontaneous de novo mutations in Drosophila melanogaster, which are crucial for many evolutionary issues, but still poorly understood. We screened for eye-color and body-color mutations that occurred in the germline cells of the first generation offspring of wild-caught females. The offspring were from matings that had...

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