Article
The rate and molecular spectrum of spontaneous mutations in Arabidopsis thaliana.
Science (New York, N.Y.) - 1 Jan 2010
Ossowski Stephan, Schneeberger Korbinian, Lucas-Lledó José Ignacio, Warthmann Norman, Clark Richard M, Shaw Ruth G, Weigel Detlef, Lynch Michael
Abstract excerpt
To take complete advantage of information on within-species polymorphism and divergence from close relatives, one needs to know the rate and the molecular spectrum of spontaneous mutations. To this end, we have searched for de novo spontaneous mutations in the complete nuclear genomes of five Arabidopsis thaliana mutation accumulation lines that had been maintained by single-seed descent for 30 generations. We...
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