Global analysis of DNA methylation variation in adipose tissue from twins reveals links to disease-associated variants in distal regulatory elements.

doi:10.1016/j.ajhg.2013.10.004

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Article

Global analysis of DNA methylation variation in adipose tissue from twins reveals links to disease-associated variants in distal regulatory elements.

American journal of human genetics - 7 Nov 2013

Grundberg Elin, Meduri Eshwar, Sandling Johanna K, Hedman Asa K, Keildson Sarah, Buil Alfonso, Busche Stephan, Yuan Wei, Nisbet James, Sekowska Magdalena, Wilk Alicja, Barrett Amy, Small Kerrin S, Ge Bing, Caron Maxime, Shin So-Youn, Lathrop Mark, Dermitzakis Emmanouil T, McCarthy Mark I, Spector Timothy D, Bell Jordana T, Deloukas Panos

Abstract excerpt

Epigenetic modifications such as DNA methylation play a key role in gene regulation and disease susceptibility. However, little is known about the genome-wide frequency, localization, and function of methylation variation and how it is regulated by genetic and environmental factors. We utilized the Multiple Tissue Human Expression Resource (MuTHER) and generated Illumina 450K adipose methylome data from 648...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 24183450
DOI: 10.1016/j.ajhg.2013.10.004
PMCID: PMC3824131

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ADCY3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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