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Article

A Genome-Wide mQTL Analysis in Human Adipose Tissue Identifies Genetic Variants Associated with DNA Methylation, Gene Expression and Metabolic Traits.

PloS one - 1 Jan 2016

Volkov Petr, Olsson Anders H, Gillberg Linn, Jørgensen Sine W, Brøns Charlotte, Eriksson Karl-Fredrik, Groop Leif, Jansson Per-Anders, Nilsson Emma, Rönn Tina, Vaag Allan, Ling Charlotte

Abstract excerpt

Little is known about the extent to which interactions between genetics and epigenetics may affect the risk of complex metabolic diseases and/or their intermediary phenotypes. We performed a genome-wide DNA methylation quantitative trait locus (mQTL) analysis in human adipose tissue of 119 men, where 592,794 single nucleotide polymorphisms (SNPs) were related to DNA methylation of 477,891 CpG sites, covering 99%...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 27322064
DOI: 10.1371/journal.pone.0157776
PMCID: PMC4913906

Genes

ADCY3
APOA5
CETP
CHRNA5
CIT
FADS2
GCKR
GPX7
LEPR
POMC
SORT1
THNSL2
ZFP57

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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