Article
Capturing functional epigenomes for insight into metabolic diseases.
Molecular metabolism - 1 Aug 2020
Allum Fiona, Grundberg Elin
Abstract excerpt
BACKGROUND: Metabolic diseases such as obesity are known to be driven by both environmental and genetic factors. Although genome-wide association studies of common variants and their impact on complex traits have provided some biological insight into disease etiology, identified genetic variants have been found to contribute only a small proportion to disease heritability, and to map mainly to non-coding regions...
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