Epigenome-Wide Study Identified Methylation Sites Associated with the Risk of Obesity.

Abstract excerpt

Here, we performed a genome-wide search for methylation sites that contribute to the risk of obesity. We integrated methylation quantitative trait locus (mQTL) data with BMI GWAS information through a SNP-based multiomics approach to identify genomic regions where mQTLs for a methylation site co-localize with obesity risk SNPs. We then tested whether the identified site contributed to BMI through Mendelian...

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• Adenylyl Cyclases
• Cyclins
• Epigenome
• Epigenomics
• HSP40 Heat-Shock Proteins
• Microtubule-Associated Proteins