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Characterizing genetic and environmental influences on variable DNA methylation using monozygotic and dizygotic twins

9 Aug 2018

Abstract excerpt

Variation in DNA methylation is being increasingly associated with health and disease outcomes. Although DNA methylation is hypothesized to be a mechanism by which both genetic and non-genetic factors can influence the regulation of gene expression, little is known about the extent to which DNA methylation at specific sites is influenced by heritable as well as environmental factors. We quantified DNA methylation...

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PMID: 30091980
DOI: 10.1371/journal.pgen.1007544

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