Article
N-acetylglucosamine-induced white-to-opaque switching in Candida albicans is independent of the Wor2 transcription factor.
Fungal genetics and biology : FG & B - 1 Jan 2014
Tong Yaojun, Cao Chengjun, Xie Jing, Ni Jian, Guan Guobo, Tao Li, Zhang Lixin, Huang Guanghua
Abstract excerpt
Candida albicans, a major opportunistic fungal pathogen of humans, can spontaneously undergo white-to-opaque switching, a prerequisite of mating. The phenotypes of white and opaque cells are heritable and bistable. The zinc-finger transcription factor Wor2 (White Opaque Regulator 2) has previously been identified as an important regulator of white-to-opaque switching. Deletion of WOR2 locks cells in the white...
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