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Ssn6 Defines a New Level of Regulation of White-Opaque Switching in Candida albicans and Is Required For the Stochasticity of the Switch

27 Jan 2016

Abstract excerpt

UNLABELLED: The human commensal and opportunistic pathogen Candida albicans can switch between two distinct, heritable cell types, named "white" and "opaque," which differ in morphology, mating abilities, and metabolic preferences and in their interactions with the host immune system. Previous studies revealed a highly interconnected group of transcriptional regulators that control switching between the two cell...

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PMID: 26814177
DOI: 10.1128/mbio.01565-15

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Ssn6 Defines a New Level of Regulation of White-Opaque Switching in Candida albicans and Is Required For the Stochasticity of the SwitchPMID 26814177Read ↗

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Regulation of white-opaque switching in Candida albicans.Semantic proximity Read ↗

The RSC (Remodels the Structure of Chromatin) complex of Candida albicans shows compositional divergence with distinct roles in regulating pathogenic traitsSemantic proximity Read ↗

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