Article
N-acetylglucosamine induces white-to-opaque switching and mating in Candida tropicalis, providing new insights into adaptation and fungal sexual evolution.
Eukaryotic cell - 1 Jun 2012
Xie Jing, Du Han, Guan Guobo, Tong Yaojun, Kourkoumpetis Themistoklis K, Zhang Lixin, Bai Feng-yan, Huang Guanghua
Abstract excerpt
Pathogenic fungi are capable of switching between different phenotypes, each of which has a different biological advantage. In the most prevalent human fungal pathogen, Candida albicans, phenotypic transitions not only improve its adaptation to a continuously changing host microenvironment but also regulate sexual mating. In this report, we show that Candida tropicalis, another important human opportunistic...
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