Article
A Set of Diverse Genes Influence the Frequency of White-Opaque Switching in Candida albicans.
G3 (Bethesda, Md.) - 5 Aug 2020
Brenes Lucas R, Lohse Matthew B, Hartooni Nairi, Johnson Alexander D
Abstract excerpt
The fungal species Candida albicans is both a member of the human microbiome and a fungal pathogen. C. albicans undergoes several different morphological transitions, including one called white-opaque switching. Here, cells reversibly switch between two states, "white" and "opaque," and each state is heritable through many cell generations. Each cell type has a distinct cellular and colony morphology and they...
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