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Article

Structure of the transcriptional network controlling white-opaque switching in Candida albicans.

Molecular microbiology - 1 Oct 2013

Hernday Aaron D, Lohse Matthew B, Fordyce Polly M, Nobile Clarissa J, DeRisi Joseph L, Johnson Alexander D

Abstract excerpt

The human fungal pathogen Candida albicans can switch between two phenotypic cell types, termed 'white' and 'opaque'. Both cell types are heritable for many generations, and the switch between the two types occurs epigenetically, that is, without a change in the primary DNA sequence of the genome. Previous work identified six key transcriptional regulators important for white-opaque switching: Wor1, Wor2, Wor3,...

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Identifiers

PMID: 23855748
DOI: 10.1111/mmi.12329
PMCID: PMC3888361

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Source receipt: pubmed, retrieved 7 Sept 2026.

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Structure of the transcriptional network controlling white-opaque switching in Candida albicans.PMID 23855748Read ↗

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