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Interlocking Transcriptional Feedback Loops Control White-Opaque Switching in Candida albicans

13 Sept 2007

Abstract excerpt

The human pathogen Candida albicans can assume either of two distinct cell types, designated "white" and "opaque." Each cell type is maintained for many generations; switching between them is rare and stochastic, and occurs without any known changes in the nucleotide sequence of the genome. The two cell types differ dramatically in cell shape, colony appearance, mating competence, and virulence properties. In...

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PMID: 17880264
DOI: 10.1371/journal.pbio.0050256

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Interlocking Transcriptional Feedback Loops Control White-Opaque Switching in Candida albicansPMID 17880264Read ↗

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