Article
White-opaque switching in Candida albicans: cell biology, regulation, and function.
Microbiology and molecular biology reviews : MMBR - 27 Jun 2024
Soll David R
Abstract excerpt
SUMMARYCandida albicans remains a major fungal pathogen colonizing humans and opportunistically invading tissue when conditions are predisposing. Part of the success of C. albicans was attributed to its capacity to form hyphae that facilitate tissue invasion. However, in 1987, a second developmental program was discovered, the "white-opaque transition," a high-frequency reversible switching system that impacted...
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