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Article

The mutate-and-map protocol for inferring base pairs in structured RNA.

Methods in molecular biology (Clifton, N.J.) - 1 Jan 2014

Cordero Pablo, Kladwang Wipapat, VanLang Christopher C, Das Rhiju

Abstract excerpt

Chemical mapping is a widespread technique for structural analysis of nucleic acids in which a molecule's reactivity to different probes is quantified at single nucleotide resolution and used to constrain structural modeling. This experimental framework has been extensively revisited in the past decade with new strategies for high-throughput readouts, chemical modification, and rapid data analysis. Recently, we...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 24136598
DOI: 10.1007/978-1-62703-667-2_4
PMCID: PMC4080707

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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