Article
MutaRNA: analysis and visualization of mutation-induced changes in RNA structure.
Nucleic acids research - 2 Jul 2020
Miladi Milad, Raden Martin, Diederichs Sven, Backofen Rolf
Abstract excerpt
RNA molecules fold into complex structures as a result of intramolecular interactions between their nucleotides. The function of many non-coding RNAs and some cis-regulatory elements of messenger RNAs highly depends on their fold. Single-nucleotide variants (SNVs) and other types of mutations can disrupt the native function of an RNA element by altering its base pairing pattern. Identifying the effect of a...
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