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Article

A major role for RCAN1 in atherosclerosis progression.

EMBO molecular medicine - 1 Dec 2013

Méndez-Barbero Nerea, Esteban Vanesa, Villahoz Silvia, Escolano Amelia, Urso Katia, Alfranca Arantzazu, Rodríguez Cristina, Sánchez Susana A, Osawa Tsuyoshi, Andrés Vicente, Martínez-González José, Minami Takashi, Redondo Juan Miguel, Campanero Miguel R

Abstract excerpt

Atherosclerosis is a complex inflammatory disease involving extensive vascular vessel remodelling and migration of vascular cells. As RCAN1 is implicated in cell migration, we investigated its contribution to atherosclerosis. We show RCAN1 induction in atherosclerotic human and mouse tissues. Rcan1 was expressed in lesional macrophages, endothelial cells and vascular smooth muscle cells and was induced by...

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Source

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Identifiers

PMID: 24127415
DOI: 10.1002/emmm.201302842
PMCID: PMC3914525

Genes

RCAN1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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