Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetic Ablation of Caveolin-1 Confers Protection Against Atherosclerosis

21 Oct 2003

Abstract excerpt

OBJECTIVE: The development of atherosclerosis is a process characterized by the accumulation of lipids in the form of modified lipoproteins in the subendothelial space. This initiating step is followed by the subsequent recruitment and proliferation of other cell types, including monocytes/macrophages and smooth muscle cells. Here, we evaluate the potential role of caveolae membrane domains in the pathogenesis of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Caveolin-1 and cellular processes
Share to Cholesterol and Lipid Metabolism
Share to Kruppel-like factors research

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 14563650
DOI: 10.1161/01.atv.0000101182.89118.e5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetic Ablation of Caveolin-1 Confers Protection Against AtherosclerosisPMID 14563650Read ↗

Genetic Evidence Supporting a Critical Role of Endothelial Caveolin-1 during the Progression of AtherosclerosisSemantic proximity Read ↗

Regulation of NO Synthesis by Caveolin-1: A Review of Its Importance in Blood Vessels, Perivascular Adipose Tissue and in AtherosclerosisSemantic proximity Read ↗

Caveolin-1-deficient mice are lean, resistant to diet-induced obesity, and show hypertriglyceridemia with adipocyte abnormalities.Semantic proximity Read ↗

Caveolin-1 deficiency stimulates neointima formation during vascular injury.Semantic proximity Read ↗

Caveolin-1 null mice are viable but show evidence of hyperproliferative and vascular abnormalities.Semantic proximity Read ↗

The Biology of Caveolae: Lessons from Caveolin Knockout Mice and Implications for Human DiseaseSemantic proximity Read ↗

Loss of Down syndrome critical region-1 leads to cholesterol metabolic dysfunction that exaggerates hypercholesterolemia in ApoE-null background.Semantic proximity Read ↗

A major role for VCAM-1, but not ICAM-1, in early atherosclerosis.Semantic proximity Read ↗

Caveolin-1 is a primary determinant of endothelial stiffening associated with dyslipidemia, disturbed flow, and ageingSemantic proximity Read ↗

Reexpression of caveolin-1 in endothelium rescues the vascular, cardiac, and pulmonary defects in global caveolin-1 knockout mice.Semantic proximity Read ↗

A major role for RCAN1 in atherosclerosis progression.Semantic proximity Read ↗

Caveolae and caveolins in the cardiovascular system.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.