Article

C-C chemokine receptor 4 deficiency exacerbates early atherosclerosis in mice

2024-08-19

Abstract excerpt

Chronic inflammation via dysregulation of T cell immune responses is critically involved in the pathogenesis of atherosclerotic cardiovascular disease. Improving the balance between proinflammatory T cells and anti-inflammatory regulatory T cells (Tregs) may be an attractive approach for treating atherosclerosis. Although C-C chemokine receptor 4 (CCR4) has been shown to mediate the recruitment of T cells to infla...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: f2ff6da8-d327-59b0-9c22-936661b9057a
DOI: 10.1101/2024.08.16.608245

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

C-C chemokine receptor 4 deficiency exacerbates early atherosclerosis in miceDOI 10.1101/2024.08.16.608245Read

Overexpression of Cytotoxic T-Lymphocyte-Associated Antigen-4 Prevents Atherosclerosis in Mice.Semantic proximity Read

Inflammatory cell recruitment in cardiovascular disease: murine models and potential clinical applicationsSemantic proximity Read

Role of Toll‐like receptor 4 in the initiation and progression of atherosclerotic diseaseSemantic proximity Read

Atypical chemokine receptor 1 deficiency reduces atherogenesis in ApoE-knockout mice.Semantic proximity Read

Xcr1 <sup>+</sup> type 1 conventional dendritic cells are essential mediators for atherosclerosis progressionSemantic proximity Read

A major role for RCAN1 in atherosclerosis progression.Semantic proximity Read

Ccr5 but not Ccr1 deficiency reduces development of diet-induced atherosclerosis in mice.Semantic proximity Read

Regulatory T Cell-Related Gene Biomarkers in the Deterioration of AtherosclerosisSemantic proximity Read

Genetic Deletion of Chemokine Receptor Ccr6 Decreases Atherogenesis inApoE-Deficient MiceSemantic proximity Read

Link between aging and atheroprotection in <i>Mif</i> -deficient atherosclerotic miceSemantic proximity Read

CCL2/CCR2 inhibition in atherosclerosis: a meta-analysis of preclinical studiesSemantic proximity Read

Myeloid Cell-Specific Deletion of LGR4 Suppresses Atherosclerotic Lesion Formation.Semantic proximity Read