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Article

Myeloid Bmal1 deletion increases monocyte recruitment and worsens atherosclerosis.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology - 1 Mar 2017

Huo Mingyu, Huang Yuhong, Qu Dan, Zhang Hongsong, Wong Wing Tak, Chawla Ajay, Huang Yu, Tian Xiao Yu

Abstract excerpt

BMAL1, the nonredundant transcription factor in the core molecular clock, has been implicated in cardiometabolic diseases in mice and humans. BMAL1 controls the cyclic trafficking of Ly6chi monocytes to sites of acute inflammation. Myeloid deficiency of Bmal1 also worsens chronic inflammation in diet-induced obesity. We studied whether myeloid Bmal1 deletion promotes atherosclerosis by enhancing monocyte...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 27927724
DOI: 10.1096/fj.201601030R
PMCID: PMC6191064

Genes

BMAL1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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