Article

LRG1 promotes atherosclerosis by activating macrophages

2024-01-25

Abstract excerpt

<h4>Background</h4> Atherosclerosis is a chronic inflammatory disease of the arterial wall characterized by the accumulation of cholesterol-rich lipoproteins in macrophages. Leucine-rich alpha-2 glycoprotein 1 (LRG1) is a circulating protein associated with inflammation, however, its role in atherosclerosis remains unclear. This study identified its role in macrophage pro-inflammatory differentiation and revealed...

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Literature Corpus work: 4aa67345-7b93-5c02-b5e7-2943eba4fb2e
DOI: 10.1101/2024.01.23.576507

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