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Article

Myosin 6 is required for iris development and normal function of the outer retina.

Investigative ophthalmology & visual science - 1 Nov 2013

Samuels Ivy S, Bell Brent A, Sturgill-Short Gwen, Ebke Lindsey A, Rayborn Mary, Shi Lanying, Nishina Patsy M, Peachey Neal S

Abstract excerpt

PURPOSE: To determine the molecular basis and the pathologic consequences of a chemically induced mutation in the translational vision research models 89 (tvrm89) mouse model with ERG defects. METHODS: Mice from a G3 N-ethyl-N-nitrosourea mutagenesis program were screened for behavioral abnormalities and defects in retinal function by ERGs. The chromosomal position for the recessive tvrm89 mutation was determined...

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Source

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Identifiers

PMID: 24106123
DOI: 10.1167/iovs.13-12887
PMCID: PMC3816618

Genes

ERG
RPE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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