Article
Identification of a new mutant allele, Grm6(nob7), for complete congenital stationary night blindness.
Visual neuroscience - 1 Jan 2015
Qian Haohua, Ji Rui, Gregg Ronald G, Peachey Neal S
Abstract excerpt
Electroretinogram (ERG) studies identified a new mouse line with a normal a-wave but lacking the b-wave component. The ERG phenotype of this new allele, nob7, matched closely that of mouse mutants for Grm6, Lrit3, Trpm1, and Nyx, which encode for proteins expressed in depolarizing bipolar cells (DBCs). To identify the underlying mutation, we first crossed nob7 mice with Grm6 nob3 mutants and measured the ERGs in...
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