Article
A Chemical Mutagenesis Screen Identifies Mouse Models with ERG Defects.
Advances in experimental medicine and biology - 1 Jan 2016
Charette Jeremy R, Samuels Ivy S, Yu Minzhong, Stone Lisa, Hicks Wanda, Shi Lan Ying, Krebs Mark P, Naggert Jürgen K, Nishina Patsy M, Peachey Neal S
Abstract excerpt
Mouse models provide important resources for many areas of vision research, pertaining to retinal development, retinal function and retinal disease. The Translational Vision Research Models (TVRM) program uses chemical mutagenesis to generate new mouse models for vision research. In this chapter, we report the identification of mouse models for Grm1, Grk1 and Lrit3. Each of these is characterized by a primary...
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