Article
Phenotypic and expression analysis of a novel spontaneous myosin VI null mutant mouse.
Experimental animals - 1 Jan 2010
Mochizuki Eiji, Okumura Kazuhiro, Ishikawa Masashi, Yoshimoto Sachi, Yamaguchi Junya, Seki Yuta, Wada Kenta, Yokohama Michinari, Ushiki Tatsuo, Tokano Hisashi, Ishii Rie, Shitara Hiroshi, Taya Choji, Kitamura Ken, Yonekawa Hiromichi, Kikkawa Yoshiaki
Abstract excerpt
In humans, hearing is a major factor in quality of life. Mouse models are important tools for the discovery of genes responsible for genetic hearing loss, often enabling analysis of the processes that regulate the onset of deafness in humans. Thus far, at least 400 deafness mutants have been discovered in laboratory mouse populations and used in the study of deafness. Here we report the discovery of a new...
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