Article
Generation, characterization, and molecular cloning of the Noerg-1 mutation of rhodopsin in the mouse.
Visual neuroscience - 1 Jan 2000
Pinto Lawrence H, Vitaterna Martha H, Shimomura Kazuhiro, Siepka Sandra M, McDearmon Erin L, Fenner Deborah, Lumayag Stephen L, Omura Chiaki, Andrews Anne W, Baker Matthew, Invergo Brandon M, Olvera Marissa A, Heffron Edward, Mullins Robert F, Sheffield Val C, Stone Edwin M, Takahashi Joseph S
Abstract excerpt
We performed genome-wide mutagenesis of C57BL/6J mice using the mutagen N-ethyl-N-nitrosourea (ENU) and screened the third generation (G3) offspring for visual system alterations using electroretinography and fundus photography. Several mice in one pedigree showed characteristics of retinal degen...
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