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Article

Genotype-phenotype correlation of mouse pde6b mutations.

Investigative ophthalmology & visual science - 1 Sept 2005

Hart Alan W, McKie Lisa, Morgan Joanne E, Gautier Philippe, West Katrine, Jackson Ian J, Cross Sally H

Abstract excerpt

PURPOSE: To identify the underlying molecular defects causing retinal degeneration in seven N-ethyl-N-nitrosourea (ENU) induced mutant alleles of the Pde6b gene and to analyze the timescale of retinal degeneration in these new models of retinitis pigmentosa. METHODS: Conformation sensitive capillary electrophoresis and DNA sequencing were used to identify the mutations in the Pde6b gene. Visual acuity testing was...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 16123450
DOI: 10.1167/iovs.05-0254

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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