Article
Polysialic acid profiles of mice expressing variant allelic combinations of the polysialyltransferases ST8SiaII and ST8SiaIV.
The Journal of biological chemistry - 20 Oct 2006
Galuska Sebastian P, Oltmann-Norden Imke, Geyer Hildegard, Weinhold Birgit, Kuchelmeister Klaus, Hildebrandt Herbert, Gerardy-Schahn Rita, Geyer Rudolf, Mühlenhoff Martina
Abstract excerpt
The post-translational modification of the neural cell adhesion molecule (NCAM) by polysialic acid (polySia) represents a remarkable example of dynamic modulation of homo- and heterophilic cell interactions by glycosylation. The synthesis of this unique carbohydrate polymer depends on the polysialyltransferases ST8SiaII and ST8SiaIV. Aiming to understand in more detail the contributions of ST8SiaII and ST8SiaIV...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
