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Article

In vitro efficacy of approved and experimental antivirals against novel genotype 3 hepatitis C virus subgenomic replicons.

Antiviral research - 1 Nov 2013

Yu Mei, Corsa Amoreena C, Xu Simin, Peng Betty, Gong Ruoyu, Lee Yu-Jen, Chan Katie, Mo Hongmei, Delaney William, Cheng Guofeng

Abstract excerpt

Infection with genotype 3 hepatitis C virus (HCV) is common throughout the world, however no direct-acting antiviral (DAA) has been approved to treat this genotype. We therefore attempted to develop novel genotype 3 replicons to facilitate the discovery and development of new HCV therapies. A novel Huh-7-derived cell line 1C but not Lunet cells enabled the selection of a few stable colonies of a genotype 3a...

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PMID: 24013001
DOI: 10.1016/j.antiviral.2013.08.018

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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