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Article

The APC p.I1307K polymorphism is a significant risk factor for CRC in average risk Ashkenazi Jews.

European journal of cancer (Oxford, England : 1990) - 1 Nov 2013

Boursi Ben, Sella Tal, Liberman Eliezer, Shapira Shiran, David Maayan, Kazanov Diana, Arber Nadir, Kraus Sarah

Abstract excerpt

BACKGROUND: The p.I1307K adenomatous polyposis coli (APC) gene variant, prevalent among Ashkenazi Jews, may increase the risk for colorectal neoplasia. We studied the clinical importance of screening for this polymorphism in 3305 Israelis undergoing colonoscopy. PATIENTS AND METHODS: Clinical data regarding potential risk factors for colorectal cancer (CRC) were collected from individuals undergoing colonoscopic...

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Identifiers

PMID: 23896379
DOI: 10.1016/j.ejca.2013.06.040

Genes

APC

Variants

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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The APC p.I1307K polymorphism is a significant risk factor for CRC in average risk Ashkenazi Jews.PMID 23896379Read ↗

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