Article
Adenomatous polyposis coli I1307K mutation in Jewish patients with different ethnicity: prevalence and phenotype.
Cancer - 15 Feb 2000
Drucker L, Shpilberg O, Neumann A, Shapira J, Stackievicz R, Beyth Y, Yarkoni S
Abstract excerpt
BACKGROUND: A new mutation, I1307K, recently was reported in the adenomatous polyposis coli (APC) gene. This mutation was found to be predominant in Ashkenazi Jews, creating a hypermutable area and predisposing the development of carcinoma. The objective of the current study was to estimate the p...
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