Article
The I1307K adenomatous polyposis coli gene variant does not contribute in the assessment of the risk for colorectal cancer in Ashkenazi Jews.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Oct 2003
Strul Hana, Barenboim Erez, Leshno Moshe, Gartner Myra, Kariv Revital, Aljadeff Eli, Aljadeff Yonathan, Kazanov Dina, Strier Ludmila, Keidar Andre, Knaani Yehudit, Degani Yaara, Alon-Baron Limor, Sobol-Dvory Hadas, Halpern Zamir, Arber Nadir
Abstract excerpt
Ashkenazi Jews with the I1307K adenomatous polyposis coli gene variant were suggested to confer a higher risk for colorectal cancer (CRC). We assessed the clinical importance of this polymorphism in Israeli Jews at average and elevated risk for CRC. Among 1,370 consecutive subjects that were examined, 975 Ashkenazi Jews were stratified into those at average risk (no personal or family history of colorectal...
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