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Article

Effect of 36 CYP2C9 variants found in the Chinese population on losartan metabolism in vitro.

Xenobiotica; the fate of foreign compounds in biological systems - 1 Mar 2014

Wang Yu-Han, Pan Pei-Pei, Dai Da-Peng, Wang Shuang-Hu, Geng Pei-Wu, Cai Jian-Ping, Hu Guo-Xin

Abstract excerpt

Abstract 1. CYP2C9 is an important member of the cytochrome P450 enzyme superfamily, with 57 CYP2C9 allelic variants being previously reported. Among these variants, we recently identified 21 novel alleles (*36-*56) in the Han Chinese population. The aim of this study was to assess the catalytic activities of 36 CYP2C9 variants found in the Chinese population toward losartan in vitro. 2. Insect microsomes...

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Identifiers

PMID: 23844998
DOI: 10.3109/00498254.2013.820007

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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