Article
In vitro functional characterization of 37 CYP2C9 allelic isoforms found in Chinese Han population.
Acta pharmacologica Sinica - 1 Nov 2013
Dai Da-peng, Wang Yu-han, Wang Shuang-hu, Geng Pei-wu, Hu Li-ming, Hu Guo-xin, Cai Jian-ping
Abstract excerpt
AIM: Cytochrome P450 2C9 (CYP2C9) is a polymorphic enzyme that is responsible for the metabolism of approximately 15% of clinically important drugs. The aim of this study was to assess the catalytic characteristics of 37 CYP2C9 allelic isoforms found in Chinese Han population on the metabolism of...
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